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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSH2D
All Species:
4.85
Human Site:
S223
Identified Species:
21.33
UniProt:
Q96JZ2
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JZ2
NP_116244.1
352
39002
S223
R
V
R
Q
Q
L
K
S
H
L
A
T
V
N
L
Chimpanzee
Pan troglodytes
XP_524147
772
86340
S643
R
V
R
Q
Q
L
K
S
H
L
T
T
V
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541968
349
38651
L224
G
K
R
V
Q
Q
Q
L
T
S
H
Q
T
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6VYH9
334
37214
S210
L
R
S
L
P
Q
T
S
Q
R
V
K
Q
R
L
Rat
Rattus norvegicus
XP_001072462
459
50493
P265
E
V
W
G
R
H
R
P
A
P
A
G
N
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q56A36
365
41301
M232
P
P
Q
L
P
P
R
M
R
L
P
S
R
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.6
N.A.
63.9
N.A.
52.5
25.4
N.A.
N.A.
N.A.
N.A.
26.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
45.3
N.A.
74.7
N.A.
65.6
39.8
N.A.
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
33.3
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
17
0
34
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
17
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
34
0
17
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
0
34
0
0
0
0
17
0
0
0
% K
% Leu:
17
0
0
34
0
34
0
17
0
50
0
0
0
34
50
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
17
34
0
% N
% Pro:
17
17
0
0
34
17
0
17
0
17
17
0
0
0
0
% P
% Gln:
0
0
17
34
50
34
17
0
17
0
0
17
17
0
17
% Q
% Arg:
34
17
50
0
17
0
34
0
17
17
0
0
17
17
0
% R
% Ser:
0
0
17
0
0
0
0
50
0
17
0
17
0
17
0
% S
% Thr:
0
0
0
0
0
0
17
0
17
0
17
34
17
0
0
% T
% Val:
0
50
0
17
0
0
0
0
0
0
17
0
34
0
0
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _